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李建伟

一、个人简介

李建伟,工学博士,教授,硕士与博士生导师,河北工业大学人工智能与数据科学学院生物信息学与计算医学研究方向带头人之一。中国计算机学会生物信息学专委会委员;中国生物工程学会会员;国家自然科学基金函评专家。2013至2014年在北京大学医学部进行访问学者研究。长期从事医学生物信息学方面研究,现主要研究方向包括:RNA-疾病关联的分析、预测与建模,非编码RNA生物标志物和药物靶点的预测与建模,人工智能算法在生物大数据挖掘中的应用及推广、医学图像分析等。近年来,在国际知名生物信息学类杂志《Nucleic Acids Research》、《Genome Biology》、《Briefings in Bioinformatics》、《Scientific Reports》、《Frontiers in Genetics》、《Frontiers in Bioengineering and Biotechnology》、《IEEE-ACM Transactions on Computational Biology and Bioinformatics》、《BMC Bioinformatics》等杂志发表高水平SCI论文20余篇,发表中文核心期刊论文10余篇。

1.教育背景:

(1)2005-09 至2009-06,河北工业大学,电工理论与新技术,博士

(2)2000-09 至2003-03,河北工业大学,计算机应用技术,硕士

(3)1994-09 至1998-07,河北工业大学,计算机及应用,学士

2.工作经历:

(1)2017-12 至今,河北工业大学,人工智能与数据科学学院,教授

(2)2009-12 至2017-11,河北工业大学,计算机科学与软件学院,副教授

(3)2005-12 至2009-11,河北工业大学,计算机科学与软件学院,讲师

(4)2003-09 至2005-11,河北工业大学,计算机科学与软件学院,助教

二、科研项目

(1)国家自然科学基金委员会,面上项目,62072154,基于多源异构信息融合的长非编码RNA功能富集分析方法研究,2021-01-01至2024-12-31,57万元,在研,主持。

(2)国家自然科学基金委员会,面上项目,81672113,反义lncRNA标志物筛选策略及其在肝脏缺血再灌注损伤中的应用研究,2017-01-01至2020-12-31,57万元,结题,主持。

(3)河北省自然科学基金委员会,面上项目,C2018202083, 基于融合结构信息的反义lncRNA靶基因筛选及其功能预测方法研究,2018-01-01至2020-12-31, 6万元,结题,主持。

三、代表性论文

(1)Li Jianwei; Ma Wei; Zeng Pan; Wang Junyi; Geng Bin; Yang Jichun; Cui Qinghua ; LncTar: a tool for predicting the RNA targets of long noncoding RNAs, Briefings in Bioinformatics, 2015, 16(5): 806-812 (中科院一区; Top期刊;ESI高被引论文)

(2)Li Jianwei; Han Xiaofen; Wan Yanping; Zhang Shan; Zhao Yingshu; Fan Rui; Cui Qinghua; Zhou Yuan ; TAM 2.0: tool for MicroRNA set analysis, Nucleic Acids Research, 2018, 46(W1): W180-W185(中科院一区; Top期刊)

(3)Li Jianwei; Zhang Shan; Wan Yanping; Zhao Yingshu; Shi Jiangcheng; Zhou Yuan; Cui Qinghua ; MISIM v2.0: a web server for inferring microRNA functional similarity based on microRNA-disease associations, Nucleic Acids Research, 2019, 47(W1): W536-W541 (中科院一区; Top期刊)

(4)Carlevaro-Fita Joana; Liu Leibo; Zhou Yuan; Zhang Shan; Chouvardas Panagiotis; Johnson Rory; Li Jianwei ; LnCompare: gene set feature analysis for human long non-coding RNAs, Nucleic Acids Research, 2019, 47(W1): W523-W529 (通讯作者;中科院一区; Top期刊)

(5)Huang Zhou; Liu Leibo; Gao Yuanxu; Shi Jiangcheng; Cui Qinghua; Li Jianwei; Zhou Yuan; Benchmark of computational methods for predicting microRNA-disease associations, genome biology, 2019, 20(202): 1-13 (通讯作者;中科院一区; Top期刊)

(6)Huang Zhou, Shi Jiangcheng, Gao Yuanxu, Cui Chunmei, Zhang Shan, Li Jianwei, Zhou Yuan, Cui Qinghua. HMDD v3.0: a database for experimentally supported human microRNA-disease associations. Nucleic Acids Research. 2019, 47(D1):D1013-D1017.(通讯作者; 中科院一区; Top期刊;ESI高被引论文)

(7)Li Jianwei, Li Jianing, Kong Mengfan, Wang Duanyang, Fu Kun, Shi Jiangcheng. SVDNVLDA: predicting lncRNA-disease associations by Singular Value Decomposition and node2vec. BMC Bioinformatics. 2021, 22(1):538.

(8)Li Jianwei, Kong Mengfan, Wang Duanyang, Yang Zhenwu, Hao Xiaoke. Prediction of lncRNA-Disease Associations via Closest Node Weight Graphs of the Spatial Neighborhood Based on the Edge Attention Graph Convolutional Network. Frontier in Genetics. 2022,12:808962.

(9)Li Jianwei, Yang Zhenwu, Wang Duanyang, Li Zhiguang. WAFNRLTG: A Novel Model for Predicting LncRNA Target Genes Based on Weighted Average Fusion Network Representation Learning Method. Frontiers in Cell and Developmental Biology. 2022, 9:820342.

(10)Li Jianwei,Wang Duanyang, Yang Zhenwu, Liu Ming. HEGANLDA: a computational model for predicting potential lncRNA-disease associations based on multiple heterogeneous networks. IEEE-ACM Transactions on Computational Biology and Bioinformatics. 2021, PP.

(11)Li Jianwei, Ma Xiaoyu, Li Xichuan, Gu Junhua. PPAI: a web server for predicting protein-aptamer interactions. BMC Bioinformatics. 2020, 21(1):236.

(12)Li Jianwei,Zhao Yingshu, Zhou Siyuan, Zhou Yuan, Lang Liying. Inferring lncRNA Functional Similarity Based on Integrating Heterogeneous Network Data. Frontiers in Bioengineering and Biotechnology. 2020, 8:27.

(13)Li Jianwei, Huang Yan, Cui Qinghua,Zhou Yuan. m6Acorr: an online tool for the correction and comparison of m6A methylation profiles[J]. BMC Bioinformatics, 2020, 21(1):31.

(14)Li Jianwei, Huang Yan, Zhou Yuan. A Mini-review of the Computational Methods Used in Identifying RNA 5-Methylcytosine Sites. Current Genomics. 2020, 21(1):3-10.

(15)Li Jianwei, Huang Yan, Yang Xiaoyue, Zhou Yiran, Zhou Yuan. RNAm5Cfinder: A Web-server for Predicting RNA 5-methylcytosine (m5C) Sites Based on Random Forest. Scientific Reports, 2018, 8: 17299.

(16)Ma Wei, Huang Chuanbo, Zhou Yuan, Li Jianwei, Cui Qinghua. MicroPattern: a web-based tool for microbe set enrichment analysis and disease similarity calculation based on a list of microbes. Scientific Reports. 2017, 7:40200

(17)Ma Wei, Zhang Lu, Zeng Pan, Huang Chuanbo, Li Jianwei, Geng Bin, Yang Jichun, Kong Wei, Zhou Xuezhong, Cui Qinghua. An analysis of human microbe-disease associations. Brief in Bioinformatics. 2017,18(1):85-97

(18)Zeng Pan, Li Jianwei, Ma Wei, Cui Qinghua. Rsite: a computational method to identify the functional sites of noncoding RNAs. Scientific Reports. 2015, 5:9179

(19)Li Jianwei, Gao Cheng, Wang Yuchen, Ma Wei, Tu Jian, Wang Junpei, Chen Zhenzhen, Kong Wei, Cui Qinghua. A bioinformatics method for predicting long noncoding RNAs associated with vascular disease. Science China Life Sciences. 2014, 57(8):852-7.

四、联系方式

地址:天津市北辰区西平道5340号河北工业大学人工智能与数据科学学院邮编:300401

联系邮箱:lijianwei@hebut.edu.cn

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